Early-Stage Ocular Hypertension Alters Retinal Ganglion Cell Synaptic Transmission in the Visual Thalamus

Axonopathy is a hallmark of many neurodegenerative diseases including glaucoma, where elevated intraocular pressure (ocular hypertension, OHT) stresses retinal ganglion cell (RGC) axons as they exit the eye and form the optic nerve. OHT causes early changes in the optic nerve such as axon atrophy, t...

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Udgivet i:Front Cell Neurosci
Main Authors: Bhandari, Ashish, Smith, Jennie C., Zhang, Yang, Jensen, Aaron A., Reid, Lisa, Goeser, Toni, Fan, Shan, Ghate, Deepta, Van Hook, Matthew J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761307/
https://ncbi.nlm.nih.gov/pubmed/31607867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00426
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