Early-Stage Ocular Hypertension Alters Retinal Ganglion Cell Synaptic Transmission in the Visual Thalamus

Axonopathy is a hallmark of many neurodegenerative diseases including glaucoma, where elevated intraocular pressure (ocular hypertension, OHT) stresses retinal ganglion cell (RGC) axons as they exit the eye and form the optic nerve. OHT causes early changes in the optic nerve such as axon atrophy, t...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Bhandari, Ashish, Smith, Jennie C., Zhang, Yang, Jensen, Aaron A., Reid, Lisa, Goeser, Toni, Fan, Shan, Ghate, Deepta, Van Hook, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761307/
https://ncbi.nlm.nih.gov/pubmed/31607867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00426
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