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NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling
The transcription factor NRF2 is a master regulator of cellular antioxidant and detoxification responses, but it also regulates other processes such as autophagy and pluripotency. In human embryonic stem cells (hESCs), NRF2 antagonizes neuroectoderm differentiation, which only occurs after NRF2 is r...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6761261/ https://ncbi.nlm.nih.gov/pubmed/31554934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50356-0 |
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