Targeted mutagenesis of the ryanodine receptor by Platinum TALENs causes slow swimming behaviour in Pacific bluefin tuna (Thunnus orientalis)

In bluefin tuna aquaculture, high mortalities of hatchery-reared juveniles occur in sea cages owing to wall collisions that are caused by high-speed swimming in panic due to changes in illuminance. Here, we report that targeted gene mutagenesis of the ryanodine receptor (RyR1b), which allows the sar...

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Publicado en:Sci Rep
Autores principales: Higuchi, Kentaro, Kazeto, Yukinori, Ozaki, Yuichi, Yamaguchi, Toshiya, Shimada, Yukinori, Ina, Yoshiaki, Soma, Satoshi, Sakakura, Yoshitaka, Goto, Rie, Matsubara, Takahiro, Nishiki, Issei, Iwasaki, Yuki, Yasuike, Motoshige, Nakamura, Yoji, Matsuura, Aiko, Masuma, Shukei, Sakuma, Tetsushi, Yamamoto, Takashi, Masaoka, Tetsuji, Kobayashi, Takanori, Fujiwara, Atushi, Gen, Koichiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761128/
https://ncbi.nlm.nih.gov/pubmed/31554877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50418-3
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