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Distinct tissue-specific roles for the disease-associated autophagy genes ATG16L2 and ATG16L1

The clear role of autophagy in human inflammatory diseases such as Crohn’s disease was first identified by genome-wide association studies and subsequently dissected in multiple mechanistic studies. ATG16L1 has been particularly well studied in knockout and hypomorph settings as well as models recap...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Khor, Bernard, Conway, Kara L, Omar, Abdifatah S, Biton, Moshe, Haber, Adam L, Rogel, Noga, Baxt, Leigh A, Begun, Jakob, Kuballa, Petric, Gagnon, John D, Lassen, Kara G, Regev, Aviv, Xavier, Ramnik J
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761021/
https://ncbi.nlm.nih.gov/pubmed/31451676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800419
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