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Targeting the 5-HT(2C) Receptor in Biological Context and the Current State of 5-HT(2C) Receptor Ligand Development

Serotonin (5-HT) 5-HT(2C) receptor (5-HT(2C)R) is recognized as a critical mediator of disease-related pathways and behaviors based upon actions in the central nervous system (CNS). Since 5-HT(2C)R is a class A G protein-coupled receptor (GPCR), drug discovery efforts have traditionally pursued the...

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Pubblicato in:Curr Top Med Chem
Autori principali: Wold, Eric A., Wild, Christopher T., Cunningham, Kathryn A., Zhou, Jia
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761005/
https://ncbi.nlm.nih.gov/pubmed/31288724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1568026619666190709101449
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