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Endo-lysosomal pathway and ubiquitin-proteasome system dysfunction in Alzheimer’s disease pathogenesis

Several lines of evidence have shown that defects in the endo-lysosomal autophagy degradation pathway and the ubiquitin-proteasome system play a role in Alzheimer’s Disease (AD) pathogenesis and pathophysiology. Early pathological changes, such as marked enlargement of endosomal compartments, gradua...

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Detalhes bibliográficos
Publicado no:Neurosci Lett
Main Authors: Cao, Jiqing, Zhong, Margaret B., Toro, Carlos A., Zhang, Larry, Cai, Dongming
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760990/
https://ncbi.nlm.nih.gov/pubmed/30890471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2019.03.016
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