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Chronic kidney disease and aging differentially diminish bone material and microarchitecture in C57Bl/6 mice

Chronic kidney disease (CKD) is a common disease of aging and increases fracture risk over advanced age alone. Aging and CKD differently impair bone turnover and mineralization. We thus hypothesize that the loss of bone quality would be greatest with the combination of advanced age and CKD. We evalu...

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Publicado no:Bone
Main Authors: Heveran, Chelsea M., Schurman, Charles, Acevedo, Claire, Livingston, Eric W., Howe, Danielle, Schaible, Eric G., Hunt, Heather, Rauff, Adam, Donnelly, Eve, Carpenter, R. Dana, Levi, Moshe, Lau, Anthony, Bateman, Ted, Alliston, Tamara, King, Karen B., Ferguson, Virginia L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760860/
https://ncbi.nlm.nih.gov/pubmed/31055118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.04.019
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