Chronic kidney disease and aging differentially diminish bone material and microarchitecture in C57Bl/6 mice

Chronic kidney disease (CKD) is a common disease of aging and increases fracture risk over advanced age alone. Aging and CKD differently impair bone turnover and mineralization. We thus hypothesize that the loss of bone quality would be greatest with the combination of advanced age and CKD. We evalu...

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Pubblicato in:Bone
Autori principali: Heveran, Chelsea M., Schurman, Charles, Acevedo, Claire, Livingston, Eric W., Howe, Danielle, Schaible, Eric G., Hunt, Heather, Rauff, Adam, Donnelly, Eve, Carpenter, R. Dana, Levi, Moshe, Lau, Anthony, Bateman, Ted, Alliston, Tamara, King, Karen B., Ferguson, Virginia L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760860/
https://ncbi.nlm.nih.gov/pubmed/31055118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.04.019
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