Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cells

BACKGROUND: A functional population of adipocyte precursors, termed adipose-derived stromal/stem cells (ASCs), is crucial for proper adipose tissue (AT) expansion, lipid handling, and prevention of lipotoxicity in response to chronic positive energy balance. We previously showed that obese human sub...

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Détails bibliographiques
Publié dans:Int J Obes (Lond)
Auteurs principaux: Ejarque, Miriam, Ceperuelo-Mallafré, Victoria, Serena, Carolina, Maymo-Masip, Elsa, Duran, Xevi, Díaz-Ramos, Angels, Millan-Scheiding, Monica, Núñez-Álvarez, Yaiza, Núñez-Roa, Catalina, Gama, Pau, Garcia-Roves, Pablo M., Peinado, Miquel A., Gimble, Jeffrey M., Zorzano, Antonio, Vendrell, Joan, Fernández-Veledo, Sonia
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760577/
https://ncbi.nlm.nih.gov/pubmed/30262812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-018-0219-6
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