Distinct transcriptional repertoire of the androgen receptor in ETS fusion-negative prostate cancer

BACKGROUND: Prostate cancer (PCa) tumors harboring translocations of ETS family genes with the androgen responsive TMPRSS2 gene (ETS+ tumors) provide a robust biomarker for detecting PCa in approximately 70% of patients. ETS+ PCa express high levels of the androgen receptor (AR), yet PCa tumors lack...

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Detalhes bibliográficos
Publicado no:Prostate Cancer Prostatic Dis
Main Authors: Berglund, Anders E., Rounbehler, Robert J., Gerke, Travis, Awasthi, Shivanshu, Cheng, Chia-Ho, Takhar, Mandeep, Davicioni, Elai, Alshalalfa, Mohammed, Erho, Nicholas, Klein, Eric A., Freedland, Stephen J., Ross, Ashley E., Schaeffer, Edward M., Trock, Bruce J., Den, Robert B., Cleveland, John L., Park, Jong Y., Dhillon, Jasreman, Yamoah, Kosj
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760558/
https://ncbi.nlm.nih.gov/pubmed/30367117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41391-018-0103-4
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