The Valosin-Containing Protein Protects the Heart Against Pathological Ca(2+) Overload by Modulating Ca(2+) Uptake Proteins

Stress-induced mitochondrial calcium (Ca(2+)) overload is a key cellular toxic effectors and a trigger of cardiomyocyte death during cardiac ischemic injury through the opening of mitochondrial permeability transition pore (mPTP). We previously found that the valosin-containing protein (VCP), an ATP...

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Détails bibliographiques
Publié dans:Toxicol Sci
Auteurs principaux: Stoll, Shaunrick, Xi, Jing, Ma, Ben, Leimena, Christiana, Behringer, Erik J, Qin, Gangjian, Qiu, Hongyu
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Molecular, Biochemical and Systems Toxicology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760276/
https://ncbi.nlm.nih.gov/pubmed/31368507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz164
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