Comparison of Zebrafish Larvae and hiPSC Cardiomyocytes for Predicting Drug-Induced Cardiotoxicity in Humans

Cardiovascular drug toxicity is responsible for 17% of drug withdrawals in clinical phases, half of post-marketed drug withdrawals and remains an important adverse effect of several marketed drugs. Early assessment of drug-induced cardiovascular toxicity is mandatory and typically done in cellular s...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Toxicol Sci
Autori principali: Dyballa, Sylvia, Miñana, Rafael, Rubio-Brotons, Maria, Cornet, Carles, Pederzani, Tiziana, Escaramis, Georgia, Garcia-Serna, Ricard, Mestres, Jordi, Terriente, Javier
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Clinical and Translational Toxicology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760275/
https://ncbi.nlm.nih.gov/pubmed/31359052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz165
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