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Inhibition of Human Liver Carboxylesterase (hCE1) by Organophosphate Ester Flame Retardants and Plasticizers: Implications for Pharmacotherapy

Organophosphate ester (OPE) flame retardants and plasticizers, consumer product additives with widespread human exposure, were evaluated for their effect on the activity of purified human liver carboxylesterase (hCE1). Four of the 15 OPEs tested had IC(50) values lower than 100 nM, including triphen...

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Vydáno v:Toxicol Sci
Hlavní autoři: Phillips, Allison L, Stapleton, Heather M
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760270/
https://ncbi.nlm.nih.gov/pubmed/31268531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz149
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