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Inhibition of Human Liver Carboxylesterase (hCE1) by Organophosphate Ester Flame Retardants and Plasticizers: Implications for Pharmacotherapy

Organophosphate ester (OPE) flame retardants and plasticizers, consumer product additives with widespread human exposure, were evaluated for their effect on the activity of purified human liver carboxylesterase (hCE1). Four of the 15 OPEs tested had IC(50) values lower than 100 nM, including triphen...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Phillips, Allison L, Stapleton, Heather M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760270/
https://ncbi.nlm.nih.gov/pubmed/31268531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz149
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