Bone loss caused by dopaminergic degeneration and levodopa treatment in Parkinson’s disease model mice

Accumulating evidence have shown the association of Parkinson’s disease (PD) with osteoporosis. Bone loss in PD patients, considered to be multifactorial and a result of motor disfunction, is a hallmark symptom that causes immobility and decreased muscle strength, as well as malnutrition and medicat...

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Udgivet i:Sci Rep
Main Authors: Handa, Kazuaki, Kiyohara, Shuichi, Yamakawa, Tomoyuki, Ishikawa, Koji, Hosonuma, Masahiro, Sakai, Nobuhiro, Karakawa, Akiko, Chatani, Masahiro, Tsuji, Mayumi, Inagaki, Katsunori, Kiuchi, Yuji, Takami, Masamichi, Negishi-Koga, Takako
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760231/
https://ncbi.nlm.nih.gov/pubmed/31551490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50336-4
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