A ribosomal protein S5 isoform is essential for oogenesis and interacts with distinct RNAs in Drosophila melanogaster

In Drosophila melanogaster there are two genes encoding ribosomal protein S5, RpS5a and RpS5b. Here, we demonstrate that RpS5b is required for oogenesis. Females lacking RpS5b produce ovaries with numerous developmental defects that undergo widespread apoptosis in mid-oogenesis. Females lacking germ...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Kong, Jian, Han, Hong, Bergalet, Julie, Bouvrette, Louis Philip Benoit, Hernández, Greco, Moon, Nam-Sung, Vali, Hojatollah, Lécuyer, Éric, Lasko, Paul
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760144/
https://ncbi.nlm.nih.gov/pubmed/31551467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50357-z
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