Tumor Cell Subtypes Based on the Intracellular Hormonal Activity in KCNJ5-Mutated Aldosterone-Producing Adenoma

Aldosterone-producing adenomas (APAs) harbor marked intratumoral heterogeneity in terms of morphology, steroidogenesis, and genetics. However, an association of biological significance of morphologically identified tumor cell subtypes and genotypes is virtually unknown. KCNJ5 mutation is most freque...

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Veröffentlicht in:Hypertension
Hauptverfasser: Yamazaki, Yuto, Omata, Kei, Tezuka, Yuta, Ono, Yoshikiyo, Morimoto, Ryo, Adachi, Yuzu, Ise, Kazue, Nakamura, Yasuhiro, Gomez-Sanchez, Celso E., Shibahara, Yukiko, Kitamoto, Takumi, Nishikawa, Tetsuo, Ito, Sadayoshi, Satoh, Fumitoshi, Sasano, Hironobu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759988/
https://ncbi.nlm.nih.gov/pubmed/30354756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.10907
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