Systemic Inflammation Rapidly Induces Reversible Atrial Electrical Remodeling: The Role of Interleukin‐6–Mediated Changes in Connexin Expression

BACKGROUND: Systemic inflammation is a strong predictor of atrial fibrillation. A key role for electrical remodeling is increasingly recognized, and experimental data suggest that inflammatory cytokines can directly affect connexins resulting in gap‐junction dysfunction. We hypothesized that systemi...

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Bibliografiska uppgifter
I publikationen:J Am Heart Assoc
Huvudupphovsmän: Lazzerini, Pietro Enea, Laghi‐Pasini, Franco, Acampa, Maurizio, Srivastava, Ujala, Bertolozzi, Iacopo, Giabbani, Beatrice, Finizola, Francesco, Vanni, Francesca, Dokollari, Aleksander, Natale, Mariarita, Cevenini, Gabriele, Selvi, Enrico, Migliacci, Nicola, Maccherini, Massimo, Boutjdir, Mohamed, Capecchi, Pier Leopoldo
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2019
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759884/
https://ncbi.nlm.nih.gov/pubmed/31423933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.011006
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