Microbe-Derived Indole Metabolite Demonstrates Potent Multidrug Efflux Pump Inhibition in Staphylococcus aureus

Efflux pumps are always at the forefront of bacterial multidrug resistance and account for the failure of antibiotics. The present study explored the potential of 2-(2-Aminophenyl) indole (RP2), an efflux pump inhibitor (EPI) isolated from the soil bacterium, to overcome the efflux-mediated resistan...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Tambat, Rushikesh, Jangra, Manoj, Mahey, Nisha, Chandal, Nishtha, Kaur, Manpreet, Chaudhary, Surbhi, Verma, Dipesh Kumar, Thakur, Krishan Gopal, Raje, Manoj, Jachak, Sanjay, Khatri, Neeraj, Nandanwar, Hemraj
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759831/
https://ncbi.nlm.nih.gov/pubmed/31620109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02153
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