The Long Noncoding RNA HEAL Regulates HIV-1 Replication through Epigenetic Regulation of the HIV-1 Promoter

A major challenge in finding a cure for HIV-1/AIDS is the difficulty in identifying and eradicating persistent reservoirs of replication-competent provirus. Long noncoding RNAs (lncRNAs, >200 nucleotides) are increasingly recognized to play important roles in pathophysiology. Here, we report the...

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Udgivet i:mBio
Main Authors: Chao, Ti-Chun, Zhang, Qiong, Li, Zhonghan, Tiwari, Shashi Kant, Qin, Yue, Yau, Edwin, Sanchez, Ana, Singh, Gatikrushna, Chang, Kungyen, Kaul, Marcus, Karris, Maile Ann Young, Rana, Tariq M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759764/
https://ncbi.nlm.nih.gov/pubmed/31551335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02016-19
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