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The dark genome and pleiotropy: challenges for precision medicine
Surprisingly we remain ignorant of the function of the majority of genes in the human and mouse genomes. The dark genome is a major obstacle to the interpretation of the function of human genetic variation and its impact on disease. At the same time, pleiotropy, how individual variants influence mul...
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| Publicat a: | Mamm Genome |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer US
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6759675/ https://ncbi.nlm.nih.gov/pubmed/31444567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-019-09813-4 |
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