A Synthetic Agonist to Vasoactive Intestinal Peptide Receptor-2 Induces Regulatory T Cell Neuroprotective Activities in Models of Parkinson’s Disease

A paradigm shift has emerged in Parkinson’s disease (PD) highlighting the prominent role of CD4(+) Tregs in pathogenesis and treatment. Bench to bedside research, conducted by others and our own laboratories, advanced a neuroprotective role for Tregs making pharmacologic transformation of immediate...

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Publicat a:Front Cell Neurosci
Autors principals: Mosley, R. Lee, Lu, Yaman, Olson, Katherine E., Machhi, Jatin, Yan, Wenhui, Namminga, Krista L., Smith, Jenell R., Shandler, Scott J., Gendelman, Howard E.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759633/
https://ncbi.nlm.nih.gov/pubmed/31619964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00421
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