Toll-Like Receptor 3 Deficiency Leads to Altered Immune Responses to Chlamydia trachomatis Infection in Human Oviduct Epithelial Cells

Reproductive tract pathology caused by Chlamydia trachomatis infection is an important global cause of human infertility. To better understand the mechanisms associated with Chlamydia-induced genital tract pathogenesis in humans, we used CRISPR genome editing to disrupt Toll-like receptor 3 (TLR3) f...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Xu, Jerry Z., Kumar, Ramesh, Gong, Haoli, Liu, Luyao, Ramos-Solis, Nicole, Li, Yujing, Derbigny, Wilbert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759307/
https://ncbi.nlm.nih.gov/pubmed/31383744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00483-19
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