Toll-Like Receptor 3 Deficiency Leads to Altered Immune Responses to Chlamydia trachomatis Infection in Human Oviduct Epithelial Cells

Reproductive tract pathology caused by Chlamydia trachomatis infection is an important global cause of human infertility. To better understand the mechanisms associated with Chlamydia-induced genital tract pathogenesis in humans, we used CRISPR genome editing to disrupt Toll-like receptor 3 (TLR3) f...

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Dades bibliogràfiques
Publicat a:Infect Immun
Autors principals: Xu, Jerry Z., Kumar, Ramesh, Gong, Haoli, Liu, Luyao, Ramos-Solis, Nicole, Li, Yujing, Derbigny, Wilbert A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759307/
https://ncbi.nlm.nih.gov/pubmed/31383744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00483-19
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