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Toll-Like Receptor 3 Deficiency Leads to Altered Immune Responses to Chlamydia trachomatis Infection in Human Oviduct Epithelial Cells

Reproductive tract pathology caused by Chlamydia trachomatis infection is an important global cause of human infertility. To better understand the mechanisms associated with Chlamydia-induced genital tract pathogenesis in humans, we used CRISPR genome editing to disrupt Toll-like receptor 3 (TLR3) f...

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Bibliografski detalji
Izdano u:Infect Immun
Glavni autori: Xu, Jerry Z., Kumar, Ramesh, Gong, Haoli, Liu, Luyao, Ramos-Solis, Nicole, Li, Yujing, Derbigny, Wilbert A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759307/
https://ncbi.nlm.nih.gov/pubmed/31383744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00483-19
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