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Toll-Like Receptor 3 Deficiency Leads to Altered Immune Responses to Chlamydia trachomatis Infection in Human Oviduct Epithelial Cells

Reproductive tract pathology caused by Chlamydia trachomatis infection is an important global cause of human infertility. To better understand the mechanisms associated with Chlamydia-induced genital tract pathogenesis in humans, we used CRISPR genome editing to disrupt Toll-like receptor 3 (TLR3) f...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Xu, Jerry Z., Kumar, Ramesh, Gong, Haoli, Liu, Luyao, Ramos-Solis, Nicole, Li, Yujing, Derbigny, Wilbert A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759307/
https://ncbi.nlm.nih.gov/pubmed/31383744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00483-19
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