Calpains of Leishmania braziliensis: genome analysis, differential expression, and functional analysis

BACKGROUND: Calpains are proteins belonging to the multi-gene family of calcium-dependent cysteine peptidases that undergo tight on/off regulation, and uncontrolled proteolysis of calpains is associated with severe human pathologies. Calpain orthologues are expanded and diversified in the trypanosom...

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Bibliographic Details
Published in:Mem Inst Oswaldo Cruz
Main Authors: Ennes-Vidal, Vítor, Vitório, Bianca da Silva, Menna-Barreto, Rubem Figueiredo Sadok, Pitaluga, André Nóbrega, Gonçalves-da-Silva, Silvia Amaral, Branquinha, Marta Helena, Santos, André Luis Souza, d’Avila-Levy, Claudia Masini
Format: Artigo
Language:Inglês
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2019
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759280/
https://ncbi.nlm.nih.gov/pubmed/31553371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760190147
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