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Long-Term Depression in the Developing Hippocampus: Low Induction Threshold and Synapse Nonspecificity

It was observed that the use of paired-pulse afferent stimulation as test stimulation (0.1–0.02 Hz) in the hippocampal CA1 area in young (1–2 week) rats, but not in older ones, led to declining synaptic activity. We show that such very low-frequency stimulation leads to long-term depression (LTD) in...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Wasling, Pontus, Hanse, Eric, Gustafsson, Bengt
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758866/
https://ncbi.nlm.nih.gov/pubmed/11880511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-05-01823.2002
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