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Enhanced Synchrony among Primary Motor Cortex Neurons in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Primate Model of Parkinson's Disease

Primary motor cortex (MI) neurons discharge vigorously during voluntary movement. A cardinal symptom of Parkinson's disease (PD) is poverty of movement (akinesia). Current models of PD thus hypothesize that increased inhibitory pallidal output reduces firing rates in frontal cortex, including M...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Goldberg, Joshua A., Boraud, Thomas, Maraton, Sharon, Haber, Suzanne N., Vaadia, Eilon, Bergman, Hagai
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758785/
https://ncbi.nlm.nih.gov/pubmed/12040070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-11-04639.2002
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