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DRPEER: A Motif in the Extracellular Vestibule Conferring High Ca(2+) Flux Rates in NMDA Receptor Channels

The high flux rate of Ca(2+) through NMDA receptor (NMDAR) channels is critical for their biological function and may depend on a Ca(2+) binding site in the extracellular vestibule. We screened substitutions of hydrophilic residues exposed in the vestibule and identified a cluster of charged residue...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Watanabe, Junryo, Beck, Christine, Kuner, Thomas, Premkumar, Louis S., Wollmuth, Lonnie P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758750/
https://ncbi.nlm.nih.gov/pubmed/12451122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-23-10209.2002
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