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Reduced Hippocampal Neurogenesis in Adult Transgenic Mice with Chronic Astrocytic Production of Interleukin-6

Postnatal neurogenesis can be modulated after brain injury, but the role of the attendant expression of inflammatory mediators in such responses remains to be determined. Here we report that transgenically directed production of interleukin-6 (IL-6) by astroglia decreased overall neurogenesis by 63%...

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書目詳細資料
發表在:J Neurosci
Main Authors: Vallières, Luc, Campbell, Iain L., Gage, Fred H., Sawchenko, Paul E.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758670/
https://ncbi.nlm.nih.gov/pubmed/11784794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-02-00486.2002
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