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ProInflammatory Mediators, Stimulators of Sensory Neuron Excitability via the Expression of Acid-Sensing Ion Channels

Tissue acidosis is an important feature of inflammation. It is a direct cause of pain and hyperalgesia. Protons activate sensory neurons mainly through acid-sensing ion channels (ASICs) and the subsequent membrane depolarization that leads to action potential generation. We had previously shown that...

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Vydáno v:J Neurosci
Hlavní autoři: Mamet, Julien, Baron, Anne, Lazdunski, Michel, Voilley, Nicolas
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758460/
https://ncbi.nlm.nih.gov/pubmed/12486159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-24-10662.2002
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