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Nicotinic Receptors Mediate Changes in Spinal Motoneuron Development and Axonal Pathfinding in Embryonic Zebrafish Exposed to Nicotine

We show that transient exposure of embryonic zebrafish to nicotine delays the development of secondary spinal motoneurons. Furthermore, there is a long-lasting alteration in axonal pathfinding in secondary motoneurons that is not ameliorated by drug withdrawal. These effects of nicotine were reverse...

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Pubblicato in:J Neurosci
Autori principali: Svoboda, Kurt R., Vijayaraghavan, Sukumar, Tanguay, Robert L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758429/
https://ncbi.nlm.nih.gov/pubmed/12486166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-24-10731.2002
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