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Glutamate But Not Glycine Agonist Affinity for NMDA Receptors Is Influenced by Small Cations

NMDA receptor currents desensitize in an agonist-dependent manner when either the glutamate or glycine agonist is subsaturating. This may result from a conformational change in the NMDA receptor protein that lowers glutamate and glycine binding site affinity induced by co-agonist binding, channel op...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Nahum-Levy, Rinat, Tam, Eyal, Shavit, Sara, Benveniste, Morris
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758286/
https://ncbi.nlm.nih.gov/pubmed/11923420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-07-02550.2002
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