Metabotropic Glutamate Receptor 1-Induced Upregulation of NMDA Receptor Current: Mediation through the Pyk2/Src-Family Kinase Pathway in Cortical Neurons

The mechanism underlying the upregulation of NMDA receptor function by group I metabotropic glutamate receptors (mGluRs), including mGluR1 and 5, is not known. Here we show that in cortical neurons, brief selective activation of group I mGluRs with (S)-3,5-dihydroxy-phenylglycine (DHPG) induced a Ca...

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Publicat a:J Neurosci
Autors principals: Heidinger, Valérie, Manzerra, Pat, Wang, Xue Qing, Strasser, Uta, Yu, Shan-Ping, Choi, Dennis W., Behrens, M. Margarita
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2002
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ARTICLE
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758206/
https://ncbi.nlm.nih.gov/pubmed/12097497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-13-05452.2002
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