p73 Is Required for Survival and Maintenance of CNS Neurons

Here, we show that the p53 family member, p73, is necessary for survival and long-term maintenance of CNS neurons, including postnatal cortical neurons. In p73−/− animals, cortical neuron number is normal at birth but decreases significantly by postnatal day 14 (P14)–P16 because of enhanced apoptosi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Pozniak, Christine D., Barnabé-Heider, Fanie, Rymar, Vladimir V., Lee, Anna F., Sadikot, Abbas F., Miller, Freda D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2002
Pynciau:
ARTICLE
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757829/
https://ncbi.nlm.nih.gov/pubmed/12427836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-22-09800.2002
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