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Caspase Activation in Hair Cells of the Mouse Utricle Exposed to Neomycin

Aminoglycoside exposure results in the apoptotic destruction of auditory and vestibular hair cells. This ototoxic hair cell death is prevented by broad-spectrum caspase inhibition. We have used in situ substrate detection, immunohistochemistry, and specific caspase inhibitors to determine which casp...

詳細記述

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書誌詳細
出版年:J Neurosci
主要な著者: Cunningham, Lisa L., Cheng, Alan G., Rubel, Edwin W
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757801/
https://ncbi.nlm.nih.gov/pubmed/12351727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-19-08532.2002
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