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12-Hydroxyeicosatetrenoate (12-HETE) Attenuates AMPA Receptor-Mediated Neurotoxicity: Evidence for a G-Protein-Coupled HETE Receptor

12-Hydroxyeicosatetraenoic acid (12-HETE) is a neuromodulator that is synthesized during ischemia. Its neuronal effects include attenuation of calcium influx and glutamate release as well as inhibition of AMPA receptor (AMPA-R) activation. Because 12-HETE reduces ischemic injury in the heart, we exa...

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Foilsithe in:J Neurosci
Main Authors: Hampson, Aidan J., Grimaldi, Maurizio
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2002
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757611/
https://ncbi.nlm.nih.gov/pubmed/11756509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-01-00257.2002
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