Altered Toll-Like Receptor Signalling in Children with Down Syndrome

Toll-like receptors (TLRs) are the key in initiating innate immune responses. TLR2 is crucial in recognising lipopeptides from gram-positive bacteria and is implicated in chronic inflammation. Children with Down syndrome (DS) are prone to infections from these pathogens and have an increased risk of...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Huggard, Dean, Koay, W. J., Kelly, Lynne, McGrane, Fiona, Ryan, Emer, Lagan, Niamh, Roche, Edna, Balfe, Joanne, Leahy, T. Ronan, Franklin, Orla, Moreno-Oliveira, Ana, Melo, Ashanty M., Doherty, Derek G., Molloy, Eleanor J.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757445/
https://ncbi.nlm.nih.gov/pubmed/31611734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4068734
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