Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin-based combination therapy with primaquine

BACKGROUND: Activation of hypnozoites of vivax malaria causes multiple clinical relapses, which contribute to the Plasmodium vivax burden and continuing transmission. Artemisinin-based combination therapy (ACT) is effective against blood-stage P. vivax but requires co-administration with primaquine...

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Bibliografski detalji
Izdano u:Malar J
Glavni autori: Daher, André, Aljayyoussi, Ghait, Pereira, Dhelio, Lacerda, Marcus V. G., Alexandre, Márcia A. A., Nascimento, Cristiana T., Alves, Júlio Castro, da Fonseca, Laís Bastos, da Silva, Diego Medeiros Dias, Pinto, Douglas Pereira, Rodrigues, Danielle Fonseca, Silvino, Ana Carolina Rios, de Sousa, Taís Nóbrega, de Brito, Cristiana Ferreira Alves, ter Kuile, Feiko O., Lalloo, David G.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757423/
https://ncbi.nlm.nih.gov/pubmed/31547827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-019-2950-4
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