Heterogeneity of cancer-associated fibroblasts and roles in the progression, prognosis, and therapy of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a lethal disease, and recurrence and metastasis are the major causes of death in HCC patients. Cancer-associated fibroblasts (CAFs), a major stromal cell type in the HCC microenvironment, promote HCC progression, and have gradually become a hot research topic in HCC...

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Bibliographic Details
Published in:J Hematol Oncol
Main Authors: Yin, Zeli, Dong, Chengyong, Jiang, Keqiu, Xu, Zhe, Li, Rui, Guo, Kun, Shao, Shujuan, Wang, Liming
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757399/
https://ncbi.nlm.nih.gov/pubmed/31547836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-019-0782-x
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