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Potential Role of Gr-1(+) CD8(+) T Lymphocytes as a Source of Interferon-γ and M1/M2 Polarization during the Acute Phase of Murine Legionella pneumophila Pneumonia

In this study, we analyzed interferon (IFN)-γ-producing cells and M1/M2 macrophage polarization in Legionella pneumophila pneumonia following anti-Gr-1 antibody treatment. Anti-Gr-1 treatment induced an M1-to-M2 shift of macrophage subtypes in the lungs and weakly in the peripheral blood, which was...

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Bibliografische gegevens
Gepubliceerd in:J Innate Immun
Hoofdauteurs: Kusaka, Yu, Kajiwara, Chiaki, Shimada, Sho, Ishii, Yoshikazu, Miyazaki, Yasunari, Inase, Naohiko, Standiford, Theodore J., Tateda, Kazuhiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: S. Karger AG 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757147/
https://ncbi.nlm.nih.gov/pubmed/30021216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000490585
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