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Biochemical and biophysical characterization of purified native CD20 alone and in complex with rituximab and obinutuzumab
CD20 is a B-lymphocyte specific integral membrane protein, an activated-glycosylated phosphoprotein expressed on the surface of B-cells and a clinically validated target of monoclonal antibodies such as rituximab, ocrelizumab, ofatumumab and obinutuzumab in the treatment of all B cell lymphomas and...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6757138/ https://ncbi.nlm.nih.gov/pubmed/31548565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50031-4 |
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