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Integration of flux measurements and pharmacological controls to optimize stable isotope-resolved metabolomics workflows and interpretation

Stable isotope-resolved metabolomics (SIRM) provides information regarding the relative activity of numerous metabolic pathways and the contribution of nutrients to specific metabolite pools; however, SIRM experiments can be difficult to execute, and data interpretation is challenging. Furthermore,...

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Publicat a:Sci Rep
Autors principals: Lorkiewicz, Pawel K., Gibb, Andrew A., Rood, Benjamin R., He, Liqing, Zheng, Yuting, Clem, Brian F., Zhang, Xiang, Hill, Bradford G.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757038/
https://ncbi.nlm.nih.gov/pubmed/31548575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50183-3
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