Androgenic effects on ventricular repolarization: A translational study from the international pharmacovigilance database to iPSC-cardiomyocytes

BACKGROUND. Male hypogonadism, arising from a range of etiologies including androgen-deprivation therapies (ADT), has been reported as a risk-factor for acquired long-QT syndrome (aLQTS) and Torsades de pointes (TdP). A full description of the clinical features of aLQTS associated with ADT and of un...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Salem, Joe-Elie, Yang, Tao, Moslehi, Javid J., Waintraub, Xavier, Gandjbakhch, Estelle, Bachelot, Anne, Hidden-Lucet, Francoise, Hulot, Jean-Sebastien, Knollmann, Bjorn C., Lebrun-Vignes, Benedicte, Funck-Brentano, Christian, Glazer, Andrew M., Roden, Dan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756939/
https://ncbi.nlm.nih.gov/pubmed/31378084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.119.040162
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