Mouse mammary tumor virus (MMTV) - like exogenous sequences are associated with sporadic but not hereditary human breast carcinoma

The inheritance of mutated suppressor genes, such as BRCA1 and BRCA2, is acknowledged as an etiological factor in hereditary breast carcinoma (HBC). Two different molecular mechanisms are possible; the Knudson’s “two hits” or the gene haploinsufficiency. Etiology of sporadic breast carcinoma (SBC) i...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Naccarato, Antonio Giuseppe, Lessi, Francesca, Zavaglia, Katia, Scatena, Cristian, Al Hamad, Mohammad A., Aretini, Paolo, Menicagli, Michele, Roncella, Manuela, Ghilli, Matteo, Caligo, Maria Adelaide, Mazzanti, Chiara Maria, Bevilacqua, Generoso
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756874/
https://ncbi.nlm.nih.gov/pubmed/31518337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102252
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