Computational analysis of naturally occurring resistance-associated substitutions in genes NS3, NS5A, and NS5B among 86 subtypes of hepatitis C virus worldwide

BACKGROUND AND OBJECTIVE: Direct-acting antivirals (DAA) facing resistance continue to be used in some areas worldwide. Thus, identifying hepatitis C virus (HCV) genotypes/subtypes and loci with certain prevalent resistance-associated substitutions (RASs) deserves attention. We investigated the glob...

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Bibliografiske detaljer
Udgivet i:Infect Drug Resist
Main Authors: Wu, Ruihong, Geng, Dongfeng, Chi, Xiumei, Wang, Xiaomei, Gao, Xiuzhu, Xu, Hongqin, Shi, Ying, Guan, Yazhe, Wang, Yang, Jin, Jinglan, Ding, Yanhua, Niu, Junqi
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2019
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756830/
https://ncbi.nlm.nih.gov/pubmed/31571951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S218584
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