Mexican BRCA1 founder mutation: Shortening the gap in genetic assessment for hereditary breast and ovarian cancer patients

The deletion of exons 9 to 12 of BRCA1 (9–12 del BRCA1) is considered a founder mutation in the Mexican population. We evaluate the usefulness of the target detection of 9–12 del BRCA1 as the first molecular diagnostic strategy in patients with Hereditary Breast and Ovarian Cancer (HBOC). We perform...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Fragoso-Ontiveros, Veronica, Velázquez-Aragón, Jose Antonio, Nuñez-Martínez, Paulina Maria, de la Luz Mejía-Aguayo, Maria, Vidal-Millán, Silvia, Pedroza-Torres, Abraham, Sánchez-Contreras, Yuliana, Ramírez-Otero, Miguel Angel, Muñiz-Mendoza, Rodolfo, Domínguez-Ortíz, Julieta, Wegman-Ostrosky, Talia, Bargalló-Rocha, Juan Enrique, Gallardo-Rincón, Dolores, Reynoso-Noveron, Nancy, Arriaga-Canon, Cristian, Meneses-García, Abelardo, Herrera-Montalvo, Luis Alonso, Alvarez-Gomez, Rosa Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756553/
https://ncbi.nlm.nih.gov/pubmed/31545835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222709
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi