High-throughput RNA-sequencing identifies mesenchymal stem cell-induced immunological signature in a rat model of corneal allograft rejection

OBJECTIVE: The immune rejection mediated by CD4(+) T cell and antigen presenting macrophages is the leading cause of corneal transplantation failure. Bone marrow-derived mesenchymal stem cells (BM-MSCs) possess robust immunomodulatory potentials, and have been shown by us and others to promote corne...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lu, Xiaoxiao, Chu, Chenchen, Liu, Xun, Gao, Yichen, Wu, Mianmian, Guo, Fang, Li, Yahong, Geng, Chao, Huang, Yue, Zhang, Yan, Zhao, Shaozhen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756551/
https://ncbi.nlm.nih.gov/pubmed/31545822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222515
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