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NMDA 2A receptors in parvalbumin cells mediate sex-specific rapid ketamine response on cortical activity

Ketamine has emerged as a widespread treatment for a variety of psychiatric disorders when used at sub-anesthetic doses, but the neural mechanisms underlying its acute action remain unclear. Here, we identified NMDA receptors containing the 2A subunit (GluN2A) on parvalbumin (PV)-expressing inhibito...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Picard, Nathalie, Takesian, Anne E., Fagiolini, Michela, Hensch, Takao K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756203/
https://ncbi.nlm.nih.gov/pubmed/30696941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0341-9
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