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Hindbrain Lactoprivic Regulation of Hypothalamic Neuron Transactivation and Gluco-regulatory Neurotransmitter Expression: Impact of Antecedent Insulin-Induced Hypoglycemia
Hindbrain energy state shapes hypothalamic control of glucostasis. Dorsal vagal complex (DVC) L-lactate deficiency is a potent glucose-stimulatory signal that causes neuronal transcriptional activation in key hypothalamic metabolic loci. The energy gauge AMPK is activated in DVC metabolic-sensory A2...
Bewaard in:
| Gepubliceerd in: | Neuropeptides |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6756167/ https://ncbi.nlm.nih.gov/pubmed/31488323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.npep.2019.101962 |
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