Granulocyte-Colony Stimulating Factor-Induced Neutrophil Recruitment Provides Opioid-Mediated Endogenous Anti-nociception in Female Mice With Oral Squamous Cell Carcinoma

Oral cancer patients report severe function-induced pain; severity is greater in females. We hypothesize that a neutrophil-mediated endogenous analgesic mechanism is responsible for sex differences in nociception secondary to oral squamous cell carcinoma (SCC). Neutrophils isolated from the cancer-i...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Scheff, Nicole N., Alemu, Robel G., Klares, Richard, Wall, Ian M., Yang, Stephen C., Dolan, John C., Schmidt, Brian L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756004/
https://ncbi.nlm.nih.gov/pubmed/31607857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00217
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