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Metabolic Response to Stress by the Immature Right Ventricle Exposed to Chronic Pressure Overload

BACKGROUND: The right ventricle exposed to chronic pressure overload exhibits hypertrophy and decompensates when exposed to stress. We hypothesize that impaired ability to increase myocardial oxidative flux through pyruvate dehydrogenase leads to hypertrophied right ventricular (RV) dysfunction when...

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Détails bibliographiques
Publié dans:J Am Heart Assoc
Auteurs principaux: Kajimoto, Masaki, Nuri, Muhammad, Isern, Nancy G., Robillard‐Frayne, Isabelle, Des Rosiers, Christine, Portman, Michael A.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755848/
https://ncbi.nlm.nih.gov/pubmed/31450994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.013169
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