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Metabolic Response to Stress by the Immature Right Ventricle Exposed to Chronic Pressure Overload

BACKGROUND: The right ventricle exposed to chronic pressure overload exhibits hypertrophy and decompensates when exposed to stress. We hypothesize that impaired ability to increase myocardial oxidative flux through pyruvate dehydrogenase leads to hypertrophied right ventricular (RV) dysfunction when...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Kajimoto, Masaki, Nuri, Muhammad, Isern, Nancy G., Robillard‐Frayne, Isabelle, Des Rosiers, Christine, Portman, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755848/
https://ncbi.nlm.nih.gov/pubmed/31450994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.013169
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