Recombinant Sj16 protein with novel activity alleviates hepatic granulomatous inflammation and fibrosis induced by Schistosoma japonicum associated with M2 macrophages in a mouse model

BACKGROUND: Potent granulomatous inflammation responses induced by schistosome eggs and resultant fibrosis are the primary causes of morbidity in schistosomiasis. Recombinant Sj16 (rSj16), a 16-kDa protein of Schistosoma japonicum produced in Escherichia coli, has been demonstrated to have novel imm...

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Publicado en:Parasit Vectors
Main Authors: Shen, Jia, Wang, Lifu, Peng, Mei, Liu, Zhen, Zhang, Beibei, Zhou, Tao, Sun, Xi, Wu, Zhongdao
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755699/
https://ncbi.nlm.nih.gov/pubmed/31547847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-019-3697-z
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