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Homoharringtonine enhances the effect of imatinib on chronic myelogenous leukemia cells by downregulating ZFX

Homoharringtonine (HHT) and imatinib have a synergistic effect in the clinical treatment of chronic myeloid leukemia (CML). The purpose of the present study was to explore the underlying mechanisms by which HHT enhanced imatinib sensitivity. K562 CML cells were treated with HHT and imatinib separate...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Wu, Jingjing, Wei, Bin, Shi, Yuye, Lu, Xueying, Ding, Yihan, Wang, Chunling, Li, Yufeng
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755169/
https://ncbi.nlm.nih.gov/pubmed/31432109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10539
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